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Incidence of self-limiting back pain in children following caudal blockade: an exploratory study.

August 28, 2010 by admin · Leave a Comment 

Incidence of self-limiting back pain in children following caudal blockade: an exploratory study.
Conclusions: The results of this study provide support that transient self-limiting back pain after caudal blockade does occur in pediatric patients. Clinically, this is useful information for physicians to provide to their patients. An exploration of factors that may be associated with back pain following caudal blockade in children is an interesting area of future research. PMID: 20716077 [PubMed - in process] (Source: Paediatric Anaesthesia)

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Horizon Scanning: FDA panel supports extension to use of duloxetine (Cymbalta)

August 27, 2010 by admin · Leave a Comment 

Horizon Scanning: FDA panel supports extension to use of duloxetine (Cymbalta)
Source: Reuters Area: News Reuters reports that a United States Food and Drug Administration (US FDA) advisory panel has supported an extension to the licensed indication for duloxetine (Cymbalta?) to include chronic back pain. The panel voted whether it effectively treated lower-back pain and osteoarthritis and voted 8-5 to approve its use for back pain, however, by a 4-9 vote they found there was insufficient data to support its use in osteoarthritis. The panellists also said there was not enough data to support a stronger 120mg dose over the current 60mg version.   The FDA will consider the advisory panel’s recommendation before making its final approval decision. Reuters notes that FDA officials said they were concerned about the impact of widening approval duloxetine, which…

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Adolescents with symptomatic laminolysis: report of two cases

August 26, 2010 by admin · Leave a Comment 

Adolescents with symptomatic laminolysis: report of two cases
Abstract  Retroisthmic cleft refers to a cleft in the lamina and is rarely reported. It was first described by Brocher, and later Wick et al. proposed the term “laminolysis” to describe the retroisthmic cleft by analogy with the nomenclature of the applied stress fracture of the pars interarticularis (spondylolysis) and the pedicle (pediculolysis). In this paper, we describe two adolescent sports players with symptomatic lumbar laminolysis. Both improved significantly after adequate conservative treatment. Knowledge of laminolysis in adolescent patients with low back pain is necessary to avoid overlooking it and late diagnosis. For correct diagnosis, multidetector three-dimensional computed tomography (CT) is suggested. In addition, magnetic resonance imaging (MRI)…

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Primary carcinoid tumor of the filum terminale—a case report

August 14, 2010 by admin · Leave a Comment 

Primary carcinoid tumor of the filum terminale—a case report
We report here about a 41-year-old patient with recurrent and progressive low back pain and bilateral S1 radiculopathy on admission. The patient underwent hemi-laminectomies of the vertebral bodies L5 and S1 and an en bloc resection of the tumor. Postoperative histopathological examination resulted in a well-differentiated intrathecal neuroendocrine tumor (carcinoid) of the terminal filum. Postoperative staging showed no pathological abnormalities and no tumor recurrence after 6 months. Even though rare, carcinoids should be considered as differential diagnosis of tumors occurring in the CNS. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00701-010-0756-9Authors Amr Abdulazim, BG-University Hospital Bergmannsheil Division of Spinal Cord Injury Bürkle-de-la-C…

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Centered, Low Back Pain - Symptoms, Treatment & Relief Options - Special Report

August 10, 2010 by admin · Leave a Comment 

Centered, Low Back Pain - Symptoms, Treatment & Relief Options - Special Report
If you suffer from lower back pain in the center of your spine, then this article was written for you. This free information can help you achieve pain relief without having surgery.

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Percutaneous Intradiscal Aspiration of a Lumbar Vacuum Disc Herniation: A Case Report

August 8, 2010 by admin · Leave a Comment 

Percutaneous Intradiscal Aspiration of a Lumbar Vacuum Disc Herniation: A Case Report
We report a case of an 83-year-old gentleman presenting with acute low back pain and radicular left lower extremity pain after golfing. A magnetic resonance imaging (MRI) of the lumbar spine revealed a low-signal-density lesion compressing the L5 nerve. A computed tomography scan was then ordered, confirming an extra-foraminal disc protrusion at the L5–S1 level, containing a focus of gas that was compressing the left L5 nerve root and communicating with the vacuum disc at L5–S1. After a failed left L5 transforaminal epidural steroid injection, the patient was brought back for a percutaneous intradiscal aspiration of the vacuum disc gas. This resulted in immediate relief for the patient. A follow-up MRI performed 2 months after the procedure found an approximate 25% reduction…

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Randomised controlled trial of integrated care to reduce disability from chronic low back pain in working and private life. Lambeek LC, van Mechelen W, Knol DL, Loisel P, Anema JR. BMJ 2010;340:c1035

August 3, 2010 by admin · Leave a Comment 

Randomised controlled trial of integrated care to reduce disability from chronic low back pain in working and private life. Lambeek LC, van Mechelen W, Knol DL, Loisel P, Anema JR. BMJ 2010;340:c1035
OBJECTIVE: To evaluate the effectiveness of an integrated care programme, combining a patient directed and a workplace directed intervention, for patients with chronic low back pain. (Source: The Spine Journal)

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Predicting prognosis in sick-listed low back pain patients: sneaking a peak inside the black box

August 3, 2010 by admin · Leave a Comment 

Predicting prognosis in sick-listed low back pain patients: sneaking a peak inside the black box
COMMENTARY ON: Jensen OK, Nielsen CV, Stengaard-Pedersen K. One-year prognosis in sick-listed low back pain patients with and without radiculopathy. Prognostic factors influencing pain and disability. Spine J 2010;10:659–75 (in this issue). (Source: The Spine Journal)

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Pfizer suspends tanezumab osteoarthritis clinical trial programme

August 2, 2010 by admin · Leave a Comment 

Pfizer suspends tanezumab osteoarthritis clinical trial programme
Source: Pfizer Area: News Pfizer Inc. has announced the suspension of the osteoarthritis clinical programme for its investigational compound tanezumab following a request by the FDA. The worldwide suspension follows a small number of reports of patients on tanezumab experiencing a worsening of osteoarthritis leading to joint replacement. To date, this adverse event has not been observed in non-osteoarthritis patient populations taking the drug. The FDA has asked the company to present its assessment of the potential implications of this adverse event for the other tanezumab clinical programmes involving non-osteoarthritis patients (cancer pain, interstitial cystitis, chronic low back pain and painful diabetic peripheral neuropathy). (Source: NeLM - News)

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Recent low back pain guidelines offer similar advice

July 28, 2010 by admin · Leave a Comment 

Recent low back pain guidelines offer similar advice
Recent clinical practice guidelines offer similar recommendations for assessing and managing low back pain, and clinicians can improve patient care by adopting these recommendations, according to a review published in the June issue of The Spine Journal, reported HealthDay News. (Source: Drug Topics - Top News)

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