Pfizer Suspends Chronic Pain Studies in Tanezumab Clinical Trial Program; Some Studies Continue in Areas of Unmet Medical Need

Pfizer Suspends Chronic Pain Studies in Tanezumab Clinical Trial Program; Some Studies Continue in Areas of Unmet Medical Need
July 19, 2010 (Pfizer) - Pfizer Inc. (NYSE: PFE) today announced, at the request of the U.S. Food and Drug Administration (FDA), the suspension of the chronic low back pain and painful diabetic peripheral neuropathy studies in the clinical program for the investigational compound tanezumab. Investigation of the compound continues in some areas of high unmet medical need, including cancer pain. read more (Source: Diabetes News from dLife.com)

FDA Panel Gives Mixed Blessing to Duloxetine for Chronic Pain

FDA Panel Gives Mixed Blessing to Duloxetine for Chronic Pain
Eli Lilly’s efforts to expand indications for duloxetine got a mixed response from an FDA advisory panel, who voted in favor of the drug for low back pain but against it for osteoarthritis. Medscape Medical News (Source: Medscape Today Headlines)

First Non-Contingent Respiratory Biofeedback Placebo versus Contingent Biofeedback in Patients with Chronic Low Back Pain: A Randomized, Controlled, Double-Blind Trial.

First Non-Contingent Respiratory Biofeedback Placebo versus Contingent Biofeedback in Patients with Chronic Low Back Pain: A Randomized, Controlled, Double-Blind Trial.
Authors: Kapitza KP, Passie T, Bernateck M, Karst M Previous studies reported that respiratory feedback (RFB) aids in alleviating chronic pain. However, to date, this adjunct treatment has not been rigorously tested against non-contingent (placebo) feedback. Forty-two patients with chronic low back pain were randomized to either RFB or non-contingent RFB. Both groups performed a daily 30-min home training for 15 consecutive days. A respiratory associated relaxation index (RI) was measured. Pain levels and a somatosensory profile were assessed before and after intervention. Additionally, pain levels were assessed 3 months after the end of intervention. Secondary outcome parameters included daily functioning, psychopathology, and suggestibility. T-tests showed higher and significant pain…

A Cost Utility Analysis of Interdisciplinary Early Intervention Versus Treatment as Usual For High-Risk Acute Low Back Pain Patients

A Cost Utility Analysis of Interdisciplinary Early Intervention Versus Treatment as Usual For High-Risk Acute Low Back Pain Patients
Chronic pain is a costly and debilitating condition that has proven difficult to treat, solely with medical interventions, due to the complex interplay of biological, psychological, and social factors in its onset and persistence. Many studies have demonstrated the effectiveness of interdisciplinary treatment that includes psychosocial interventions for low back pain. Nevertheless, these interventions continue to be under-utilized due to concerns of cost and applicability. The present study utilized a cost utility analysis to evaluate effectiveness and associated costs of interdisciplinary early intervention for individuals with acute low back pain that was identified as high-risk for becoming chronic. Treatment effectiveness was evaluated using a standard pain measure and quality-adjusted…

What is Chronic Back Pain?

What is Chronic Back Pain?
Chronic pain is when there seems to be no reason for the pain, in that doing something about it, as in moving the hand, will prevent further injury to the body. Chronic pain is identified as pain lasting for more than three to six months after different therapies and drugs have been used to address the pain with no long term relief. When you know your back and how it works, addressing your physician with your symptoms and being aware of the source can be beneficial to relief from chronic back pain.

Do You Have Severe Lower Right Back Pain? Get Quick and Effective Relief For Back Pain!

Do You Have Severe Lower Right Back Pain? Get Quick and Effective Relief For Back Pain!
So you have severe lower right back pain and you want permanent relief from it? Very often back pain sufferers can not enjoy the things, that others take for granted, like sports, hiking, playing with the kids. Fortunately you don’t have to suffer from severe and chronic pain no longer.

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Evidences of memory dysfunction and maladaptive coping in chronic low back pain and rheumatoid arthritis patients: challenges for rehabilitation.

Evidences of memory dysfunction and maladaptive coping in chronic low back pain and rheumatoid arthritis patients: challenges for rehabilitation.
CONCLUSIONS: Both groups of chronic pain patients are likely to have impaired memory. Maladaptive coping correlates to LBP, but not to RA. A further controlled protocol must include greater sample of patients. By analyzing memory deficits of chronic pain patients, clinicians could establish targeted rehabilitation programs and outcomes. Some techniques are discussed. PMID: 19935619 [PubMed - as supplied by publisher] (Source: European Journal of Physical and Rehabilitation Medicine)

American Society Of Anesthesiologists Urges Americans To Fight Back Against Pain

American Society Of Anesthesiologists Urges Americans To Fight Back Against Pain
Whether the result of injury, illness or a chronic condition, 70 million Americans experience pain annually. The individual pain sufferer may experience a diminished quality of life, lack of mobility and added stress. For the country as a whole, pain has far-reaching cost implications. It is estimated that more than 140 million work days are lost because of back pain. (1,2) As a result of chronic pain and the loss in productivity that it causes, approximately $60-100 billion is wasted each year… (Source: Health News from Medical News Today)

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Minimally Invasive Surgery Corrects Scoliosis And Relieves Retired Teacher’s Chronic Pain

Minimally Invasive Surgery Corrects Scoliosis And Relieves Retired Teacher’s Chronic Pain
Carole Riggs, a retired teacher and school principal, points to her work during one Christmas vacation bending, twisting and sitting on the floor to create games and teaching aids as the primary culprit behind many years of back pain. Burak M. Ozgur, M.D. (Source: Neurology / Neuroscience News From Medical News Today)

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62-Year-Old Man Becomes First Patient In China Implanted With Rechargeable Neurostimulator For Chronic Pain

62-Year-Old Man Becomes First Patient In China Implanted With Rechargeable Neurostimulator For Chronic Pain
St. Jude Medical, Inc. (NYSE:STJ) announced that a 62-year-old man from Shenzhen, Guangdong province has become the first patient in China to be implanted with the Eon™ neurostimulator, a rechargeable device used to help manage chronic pain. Despite prior back surgeries, the patient suffered from chronic back pain for more than a decade. (Source: Health News from Medical News Today)

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