FDA Panel Gives Mixed Blessing to Duloxetine for Chronic Pain
August 28, 2010 by admin · Leave a Comment
FDA Panel Gives Mixed Blessing to Duloxetine for Chronic Pain
Eli Lilly’s efforts to expand indications for duloxetine got a mixed response from an FDA advisory panel, who voted in favor of the drug for low back pain but against it for osteoarthritis. Medscape Medical News (Source: Medscape Today Headlines)
Horizon Scanning: FDA panel supports extension to use of duloxetine (Cymbalta)
August 27, 2010 by admin · Leave a Comment
Horizon Scanning: FDA panel supports extension to use of duloxetine (Cymbalta)
Source: Reuters Area: News Reuters reports that a United States Food and Drug Administration (US FDA) advisory panel has supported an extension to the licensed indication for duloxetine (Cymbalta?) to include chronic back pain. The panel voted whether it effectively treated lower-back pain and osteoarthritis and voted 8-5 to approve its use for back pain, however, by a 4-9 vote they found there was insufficient data to support its use in osteoarthritis. The panellists also said there was not enough data to support a stronger 120mg dose over the current 60mg version. The FDA will consider the advisory panel’s recommendation before making its final approval decision. Reuters notes that FDA officials said they were concerned about the impact of widening approval duloxetine, which…
Correct Application Of MRI: helps find causes of lower back pain
August 17, 2010 by admin · Leave a Comment
Correct Application Of MRI: helps find causes of lower back pain
Low back pain is extremely common in Western society.1 It is second only to upper respiratory illness as a symptom-related reason for visits to the doctor.2 (Source: Diagnostic Imaging)
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Lower Muscle Back Pain Symptoms, and How to Cure It!
August 11, 2010 by admin · Leave a Comment
Lower Muscle Back Pain Symptoms, and How to Cure It!
The Real Issues: Many doctors miss the main concerns with lower back pain. It could also just be lower muscle back pain as well, you also know that back pain is common, but many doctors do not understand why. The answer is quite simple.
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Cost of Low Back Pain - Symptoms, Treatment & Pain Relief - Braces For Support
August 10, 2010 by admin · Leave a Comment
Cost of Low Back Pain - Symptoms, Treatment & Pain Relief - Braces For Support
What is the cost of low back pain? This free article looks at this from a emotional and monetary stand point. This information can help you get pain relief as well without spending an arm and a leg.
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Pfizer suspends tanezumab osteoarthritis clinical trial programme
August 2, 2010 by admin · Leave a Comment
Pfizer suspends tanezumab osteoarthritis clinical trial programme
Source: Pfizer Area: News Pfizer Inc. has announced the suspension of the osteoarthritis clinical programme for its investigational compound tanezumab following a request by the FDA. The worldwide suspension follows a small number of reports of patients on tanezumab experiencing a worsening of osteoarthritis leading to joint replacement. To date, this adverse event has not been observed in non-osteoarthritis patient populations taking the drug. The FDA has asked the company to present its assessment of the potential implications of this adverse event for the other tanezumab clinical programmes involving non-osteoarthritis patients (cancer pain, interstitial cystitis, chronic low back pain and painful diabetic peripheral neuropathy). (Source: NeLM - News)
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Doubt Cast on Common Back Pain Management
August 1, 2010 by admin · Leave a Comment
Doubt Cast on Common Back Pain Management
Many people with arthritis-related back pain might be prevented from getting long-lasting pain relief under the current management guidelines, US researchers said Friday.Source: Reuters Health Related MedlinePlus Pages: Arthritis, Back Pain (Source: MedlinePlus Health News)
Burden of childhood-onset arthritis
July 28, 2010 by admin · Leave a Comment
Burden of childhood-onset arthritis
Juvenile arthritis comprises a variety of chronic inflammatory diseases causing erosive arthritis in children, often progressing to disability. These children experience functional impairment due to joint and back pain, heel pain, swelling of joints and morning stiffness, contractures, pain, and anterior uveitis leading to blindness. As children who have juvenile arthritis reach adulthood, they face possible continuing disease activity, medication-associated morbidity, and life-long disability and risk for emotional and social dysfunction. In this article we will review the burden of juvenile arthritis for the patient and society and focus on the following areas: patient disability; visual outcome; other medical complications; physical activity; impact on HRQOL; emotional impact; pain and …
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Clinical Prediction Rules Currently Fail to Predict
July 22, 2010 by admin · Leave a Comment
Clinical Prediction Rules Currently Fail to Predict
Many musculoskeletal conditions represent only symptoms related to a myriad of possible underlying pathologies. For example, due to the many underlying causes of low back pain, no single treatment option including drugs, surgery, exercise or spinal manipulation successfully treats all patients. (Source: ChiroACCESS: Tools for Better Patient Care)
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Trial Shows Glucosamine No Better Than Placebo For Lower Back Pain
July 19, 2010 by admin · Leave a Comment
Trial Shows Glucosamine No Better Than Placebo For Lower Back Pain
A controlled trial in Norway found that the popular dietary supplement glucosamine was no better than placebo at reducing pain-related disability in people with lower back pain with degenerative lumbar osteoarthritis (OA). You can read about the trial in a report by lead investigator Dr Philip Wilkens of the Department of Orthopaedics at Oslo University Hospital in the 7 July online issue of JAMA… (Source: Health News from Medical News Today)
