Variations in brain volume and regional morphology associated with chronic pain
January 13, 2009 by admin
Variations in brain volume and regional morphology associated with chronic pain
Abstract Various peripheral and spinal mechanisms have been hypothesized to contribute to pain amplification and chronicity. However, the role of the brain in chronic pain states remains to be fully elucidated. Functional brain imaging techniques, such as positron emission tomography and functional magnetic resonance imaging, have frequently been used to investigate brain activity during acute/experimental pain perception, which has helped to establish the notion of the human pain network. In the context of chronic pain, the assessment of brain chemistry (by way of spectroscopy) and brain morphology is of growing interest, and there is a quickly expanding body of evidence that persons with chronic pain conditions, including chronic low back pain, chronic tension-type heada…
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