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Patients with pain disorder show gray-matter loss in pain-processing structures: a voxel-based morphometric study

January 21, 2009 by admin 

Patients with pain disorder show gray-matter loss in pain-processing structures: a voxel-based morphometric study
Conclusions: In the context of similar results in patients with other functional pain syndromes, such as fibromyalgia and chronic back pain, we suggest that structural changes in fronto-limbic brain circuits represent not only an objective marker of these pain syndromes but also constitute a critical pathophysiological element. These findings represent a further proof of the important role of central changes in pain disorder. (Source: Psychosomatic Medicine)

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