Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP
March 21, 2010 by admin
Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP
Abstract Steroid therapy appeared to be a standard treatment for autoimmune pancreatitis (AIP), although some AIP patients improve spontaneously. The indications for steroid therapy in AIP patients are symptoms such as obstructive jaundice, abdominal pain, and back pain, and the presence of symptomatic extrapancreatic lesions. Before steroid therapy, jaundice should be managed by biliary drainage in patients with obstructive jaundice, and blood glucose levels should be controlled in patients with diabetes mellitus. For the initial oral prednisolone dose for induction of remission, 0.6 mg/kg/day is recommended. The initial dose is administered for 2â4 weeks, and the dose is tapered by 5 mg every 1â2 weeks, based on changes in the clinical manifestatio…
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