Clinical and radiographic response to a local infliximab injection in a patient with chronic sacroiliitis.
February 8, 2009 by admin
Clinical and radiographic response to a local infliximab injection in a patient with chronic sacroiliitis.
Authors: O’Shea FD, Haroon N, Salonen DC, Inman RD Background A 49-year-old man presented to a rheumatology clinic with a 2-month history of low back pain. The pain seemed to be inflammatory in origin, with nocturnal occurrence and substantial early morning stiffness. The patient was previously well, with no history of psoriasis, inflammatory bowel disease or iritis.Investigations Physical examination, anteroposterior X-ray of the pelvis, isotope bone scan, CT and MRI of the sacroiliac joints, measurement of serum inflammatory markers, HLA-B27 testing, routine and mycobacterial culture of the sacroiliac joint fluid aspirate, tuberculosis skin testing and chest X-ray.Diagnosis An HLA-B27-negative patient with chronic unilateral sacroiliitis refractory to conventional management.Manageme…
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